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Exploring Strong Interactions in Proteins with Quantum Chemistry and Examples of Their Applications in Drug Design

Fig 4

Amide bridge interactions between amino acids Asn and Gln.

A) Interaction structure of amide bridge for the Asn-Asn interaction. B) Interaction structure of amide bridge for the Asn-Gln interaction. C) Interaction structure of amide bridge for the Gln-Gln interaction. The energies of aa amide bridge interactions are in the range -65 to -70 kJ/mol.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0137113.g004