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Osteoprotective Effect of Echinocystic Acid, a Triterpone Component from Eclipta prostrata, in Ovariectomy-Induced Osteoporotic Rats

Fig 2

Effects of EA on bone formation and resorption parameters.

(A) Effects of E2 and EA on serum alkaline phosphatase (ALP). (B) Effects of E2 and EA on serum osteocalcin (OC). (C) Effects of E2 and EA on urinary deoxypyridinoline (DPD/Cr). E2 (25 μg/kg/day); EA-L (1 mg/kg/day); EA-M (5 mg/kg/day), EA-H (15 mg/kg/day). n = 10; * p < 0.05, ** p < 0.01 vs OVX; ## p < 0.01 vs Sham.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0136572.g002