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Bioinformatic Challenges in Clinical Diagnostic Application of Targeted Next Generation Sequencing: Experience from Pheochromocytoma

Fig 5

Venn diagram of overlapping variants between the two sequencing runs, total (all variants available at bases annotated for the 11 included genes) and non synonymous remaining variants after filtering synonymous variants with no calculated splice site disruption.

MSR; MiSEQ Reporter, CLC; CLC Genomics Workbench, and ICP; In-house custom pipeline.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0133210.g005