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Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish

Fig 5

Endogenous gene expression matches the gene-trap GFP expression pattern for agtpbp1 and eps15L1 lines.

(A) The GFP pattern in a representative 6 dpf embryo from the agtpbp1fcc301 line. (B-D) WISH of agtpbp1 at 6 dpf. Lateral line cells (*), epiphysis (arrowhead) and nasal pit (arrow) are indicated. (C-D) Magnified views of regions of the embryo shown in B. (E) The GFP pattern in a representative 6 dpf embryo from line eps15L1fcc436. (F-I) WISH of eps15L1 at 6 dpf. Pancreas (under *), kidney (arrowhead) and skin cells (arrows) are indicated. (G-I) Magnified views of regions of the embryo shown in F.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0131908.g005