Computational Approaches for Decoding Select Odorant-Olfactory Receptor Interactions Using Mini-Virtual Screening
Fig 8
Heat map of the odorant profile of 10 human-mouse OR pairs.
X-axis shows the human-mouse OR pair and the sequence identity between human-mouse OR pairs. Y-axis indicates the number of 130 odorants used in this study. The heat map is obtained using the gscore (kcal/mol) of interaction of each ligand to the given receptor. The scores have been normalized between 0 to 1 as shown in the scale. The odorants for which experimental data are available (Steroids, Helional, Undecanal, Eugenol and Citronellol) have been marked with a red arrow. Insect ORs have been marked in a green rectangular box. The heat map has been generated using R software.