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Design, Synthesis and Structure-Activity Relationship Studies of Novel Survivin Inhibitors with Potent Anti-Proliferative Properties

Fig 8

Heat map showing the GI50 values (nM) for UC-112 and three analogs in the NCI-60 screening.

High intensity (blue) cells indicate high activity and low intensity (red) cells indicate low activity. Average GI50 values were calculated for each compound, separately.

Fig 8

doi: https://doi.org/10.1371/journal.pone.0129807.g008