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Cambinol, a Novel Inhibitor of Neutral Sphingomyelinase 2 Shows Neuroprotective Properties

Fig 9

Effect of cambinol on TNF-α-induced decrease in dendrite length of rat primary hippocampal neurons.

Cells were treated with cambinol (0.1–30 μM) and TNF-α (100 ng/ml) for 18 h. Dendrite length was assessed by imaging of MAP-2 stained cells using Neurolucida software. Results shown are the average of 5–6 experiments. Error bars correspond to S.E.M. * p < 0.05 and ** p < 0.01.

Fig 9

doi: https://doi.org/10.1371/journal.pone.0124481.g009