The In Vitro and In Vivo Anti-Cancer Activities of a Standardized Quassinoids Composition from Eurycoma longifolia on LNCaP Human Prostate Cancer Cells
Fig 1
Dose-dependent cytotoxicity of SQ40 on human normal and prostate cancer cell lines.
RWPE-1 normal prostate cells (black), WRL 68 normal liver cells (blue), LNCaP (red) and PC-3 prostate cancer cells (green) were treated with increasing concentrations (2.5–100 μg/mL) of SQ40 for 72 hours and cell viability was measured using MTT reduction assay. Data were expressed as mean ± SEM of four independent experiments. IC50 values of SQ40 on RWPE-1, WRL 68, LNCaP and PC-3 cells at 72 hours treatment were 59.26 μg/mL, 27.69 μg/mL, 5.97 μg/mL and 87.94 μg/mL, respectively.