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The Unrecognized Effects of Phosphodiesterase 4 on Epithelial Cells in Pulmonary Inflammation

Fig 8

In vitro transmigration assay of human PMNs through a pulmonary epithelial monolayer.

PMNs or epithelium were treated with rolipram/roflumilast and migration of PMNs through human epithelium measured. Migration of PMNs was initiated through the chemokine CXCL2/3 in all wells. Data are presented as mean ± SD; n≥4; *P < 0.05 vs. control.

Fig 8

doi: https://doi.org/10.1371/journal.pone.0121725.g008