The Unrecognized Effects of Phosphodiesterase 4 on Epithelial Cells in Pulmonary Inflammation
Fig 6
Gene expression and protein levels of PDE4B and PDE4D in lungs of mice.
The impact of rolipram and roflumilast on transcription and translation of PDE4B (A) and PDE4D (B) was determined in the lungs of mice. Data are presented as mean ± SD; n = 6 without LPS; n≥7 with LPS; representative Western blot analyses of four independent experiments (for whole western blots see S1 Fig); *P < 0.05 vs. control without LPS; #P < 0.05 vs. control with LPS inhalation.