The Unrecognized Effects of Phosphodiesterase 4 on Epithelial Cells in Pulmonary Inflammation
Fig 4
Chemokine levels in the BAL are reduced by rolipram and roflumilast.
LPS inhalation increased all chemokine levels and the administration of the PDE4-inhibitors decreased this effect. Data are presented as mean ± SD; n = 4 without LPS; n≥6 with LPS; *P < 0.05 vs. control without LPS; #P < 0.05 vs. control with LPS inhalation; °P < 0.05 vs. rolipram.