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The Unrecognized Effects of Phosphodiesterase 4 on Epithelial Cells in Pulmonary Inflammation

Fig 2

Impact of PDE-inhibitors on PMN infiltration into the lungs identified by immunohistochemistry.

Neutrophils were stained with a specific marker and appear brown in histology (rat anti-mouse neutrophil, clone 7/4) (original magnification, x63). Images are representatives of n = 4 experiments. Alveolar septa of the different conditions were measured. Data are presented as mean ± SD; n = 6; *P < 0.05 vs. control without LPS; #P < 0.05 vs. control with LPS; °P < 0.05 vs. rolipram.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0121725.g002