Magnolol Administration in Normotensive Young Spontaneously Hypertensive Rats Postpones the Development of Hypertension: Role of Increased PPAR Gamma, Reduced TRB3 and Resultant Alleviative Vascular Insulin Resistance
Fig 2
A and B, Representative blots and quantitative densitometry of PPARγ and TRB3 in the aortic segments from control or magnolol-treated WKY and SHRs.
C and D, Representative blots of total Akt and phosphorylated Akt and the ratio of phosphorylated Akt/total Akt, total eNOS and phosphorylated eNOS and the ratio of phosphorylated eNOS/total eNOS in the aortic segments with insulin treatment from control or magnolol-treated WKY and SHRs, and NO release (E) in the rat aortas. Data obtained from quantitative densitometry were presented as mean ± SEM of at least 5 independent experiments. M, magnolol. *P<0.05 vs. WKY, #P<0.05 vs. SHRs.