The Molecular Mechanism of Bisphenol A (BPA) as an Endocrine Disruptor by Interacting with Nuclear Receptors: Insights from Molecular Dynamics (MD) Simulations
Fig 5
Cartoon representations of the active and inactive conformation of hERα.
a) The active state of the protein with H12 in red cartoon and coactivator in green cartoon; b) The inactive state of the protein with H12 (red) covered the shallow groove which would be occupied by the coactivator.