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Potential Biomarkers of Fatigue Identified by Plasma Metabolome Analysis in Rats

Fig 5

Relative concentrations of plasma metabolites related to the TCA cycle, urea cycle and proline metabolism, and BCAA metabolism.

Relative amounts of each metabolite in the control (C, n = 5), food-restricted (R, n = 5), and fatigued (F, n = 6) groups are shown and expressed as a percent of the control group. Data are presented as mean ± S.D. P < 0.05, significantly different than the control group. §P < 0.05, significantly different between the food-restricted and fatigued group.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0120106.g005