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2H,3H-Decafluoropentane-Based Nanodroplets: New Perspectives for Oxygen Delivery to Hypoxic Cutaneous Tissues

Fig 6

Topical treatment with OLND gel formulation effectively enhances oxy-Hb levels in vivo.

The shaved hind limbs of nine anesthetized mice were monitored by photoacoustics for oxy-Hb and deoxy-Hb levels before (0 min, upper row), during (0–10 min, central row) and after (10 min, lower row) topical treatment with OSS (first column), OLND (second column) and OFND (third column) gel formulations. White/red pixels: oxy-Hb; blue pixels: deoxy-Hb. Data are shown as representative images from three independent experiments (three mice per experiment) with similar results.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0119769.g006