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Genome-Wide Association Study in an Admixed Case Series Reveals IL12A as a New Candidate in Behçet Disease

Fig 5

SNP association plot for Behçet’s susceptibility-associated region of Chromosome 18q22.3.

Dots represent GWAS P-values (EMMAX approach) and positions of SNPs found within the 18q22.3 locus. The top SNP, i.e. rs17087141, is denoted by a diamond. Different colours indicate varying degrees of pair-wise linkage disequilibrium (1000Genomes CEU) between the top SNP and all other genotyped SNPs. Genetic coordinates are per 1000 Genomes Nov 2010-CEU. Bottom, LD heat map based on D’ values from the combined population under study including all SNPs in the 500Kb region.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0119085.g005