Genome-Wide Association Study in an Admixed Case Series Reveals IL12A as a New Candidate in Behçet Disease
Fig 4
SNP association plot for Behçet’s susceptibility-associated region of chromosome 6q25.3.
Dots represent GWAS P-values (EMMAX approach) and positions of SNPs found within the 6q25.3 locus. The top SNP, i.e. rs8187722, is denoted by a diamond. Different colours indicate varying degrees of pair-wise linkage disequilibrium (1000 Genomes Nov 2010 CEU) between the top SNP and all other genotyped SNPs. Genetic coordinates are per 1000 Genomes Nov 2010-CEU. Bottom, LD heat map based on D’ values from the combined population under study including all SNPs in the 500Kb region.