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Pre-Transplant Donor-Specific T-Cell Alloreactivity Is Strongly Associated with Early Acute Cellular Rejection in Kidney Transplant Recipients Not Receiving T-Cell Depleting Induction Therapy

Fig 3

Receiver operating characteristic (ROC) curve estimating the most likely time-frame of TCMR associated with pre-transplant T-cell sensitization.

Positive pre-transplant T-cell sensitization was a highly sensitive and specific predictor of the advent of TCMR during the first 8 weeks (1.65 months) after transplantation (AUC = 0.701; p = 0.065).

Fig 3

doi: https://doi.org/10.1371/journal.pone.0117618.g003