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Pre-Transplant Donor-Specific T-Cell Alloreactivity Is Strongly Associated with Early Acute Cellular Rejection in Kidney Transplant Recipients Not Receiving T-Cell Depleting Induction Therapy

Fig 1

Pre-transplant d-s T-cell alloreactivity positively correlates with recipient age and with HLA class I mismatch.

A. Correlation between pre-transplant frequency of donor-specific IFN-γ T-cell spots and recipient age (years) (R = 0.349, p = 0.001). B. Correlation between pre-transplant frequency of donor-specific IFN-γ T-cell spots and class I HLA mismatches (R = 0.207, p = 0.05).

Fig 1

doi: https://doi.org/10.1371/journal.pone.0117618.g001