Transcriptome Analysis of Scorpion Species Belonging to the Vaejovis Genus
Fig 3
Putative calcium channel toxins found in Vaejovis.
The peptide length (aa) always refers to the confirmed (when the peptide has been isolated from the venom) or software-predicted mature peptides. The given percentages of identity (%I) correspond to the mature peptides only, and refer to the first sequence. The predicted signal peptides are shown underlined, the propeptides in italics and bold. A) Sequence alignment of the three-disulfide-bridged putative calcinsVpCaTx1 from V. punctatus and ViCaTx1 from V. intrepidus with imperatoxin (UniProt:P59868) from P. imperator, maurocalcin (UniProt:P60254) from S. maurus palmatus, opicalcin-1 (UniProt:P60252) and opicalcin-2 (UniProt:P60253) from Opistophthalmus carinatus, UyCaTx20 (Calcium-channel toxin-like 20, UniProt:AGA82762) from U. yaschenkoi and hadrucalcin (UniProt:B8QG00) from H. gertschi. B) The precursors of the two-disulfide-bridged putative calcins VmCaTx1 and VmCaTx2 from V. mexicanus and VpCaTx2 from V. punctatus, are compared to previously reported sequences of their kind: LaIT1 (UniProt:P0C5F2) from L. australasiae, and U1-LITX-Lw1a (UniProt:P0DJ08) from L. waigiensis.