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Enzymes from Fungal and Plant Origin Required for Chemical Diversification of Insecticidal Loline Alkaloids in Grass-Epichloë Symbiota

Figure 8

Summarized loline-alkaloid biosynthetic pathway.

Labeled arrows are for steps that contribute to diversity of the lolines. Presence or absence of functional copies of lolO, lolN, lolM, or lolP, or a plant acetyltransferase activity, determine which alkaloids accumulate in the symbiotic plant as the pathway end-products.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0115590.g008