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Abieslactone Induces Cell Cycle Arrest and Apoptosis in Human Hepatocellular Carcinomas through the Mitochondrial Pathway and the Generation of Reactive Oxygen Species

Figure 5

The effect of abieslactone on the MMP in HepG2 and SMMC7721 cells.

(A) The MMP of HepG2 and SMMC7721 cells treated with abieslactone at different concentrations was analyzed by flow cytometry. (B) The loss of the MMP in HepG2 and SMMC7721 cells following abieslactone treatment in a dose dependent manner. The data are expressed as the means ± SEM for three independent experiments with similar results. *P<0.05 vs. the untreated control.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0115151.g005