Phylogenetic Profiling: How Much Input Data Is Enough?
Figure 5
Predictive accuracy of phylogenetic profiling was not affected when we used many strains of the same organism.
We used 31 strains of Escherichia coli and we added to this set: A) 31 random organisms, B) 62 random organisms, C) 93 random organisms, and D) 124 random organisms. Each plot in a panel corresponds either to the combination of the 31 E. coli strains and the randomly selected organisms (left) or just the randomly selected organisms (right). Each boxplot summarizes AUPRC scores for GO terms in the dataset indicated on the x-axis. Lower, mid, and upper horizontal lines denote the first quartile, median and the third quartile, respectively; vertical lines reach 1.5 interquartile range from the respective quartile or the extreme value, whichever is closer. Each plot summarizes the results for ten independent random organism selections.