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The Protective Effect of Esculentoside A on Experimental Acute Liver Injury in Mice

Figure 8

Effects of EsA on cell apoptosis at 12 hours post-CCl4 injection.

Liver tissues sections were stained with TUNEL method (Magnification, ×200). There were no obvious difference for rates of positive TUNEL stained cells between the Injury and Injury+EsA groups (A). The activity of Bax, Caspase-3 and cleaved Caspase-3 were determined by western blot. Relative protein levels were quantified by densitometry and expressed as optical density ratio (B). The values presented are the means ± standard error of the mean (n = 6). #P<0.05, ##P<0.01 versus the Control group.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0113107.g008