Methyllycaconitine Alleviates Amyloid-β Peptides-Induced Cytotoxicity in SH-SY5Y Cells
Figure 6
MLA inhibition of Aβ-induced autophagy is mediated by mTOR signal pathway in SH-SY5Y cells.
(A) After exposure to different doses of Aβ25–35, the level of phosphorylated p70S6K, a mTOR complex 1 substrate, was evaluated by western blot analysis. Signals were quantified by densitometry. (B) Western blot analysis of level of phosphorylated p70S6K after exposure to 10 µM Aβ25–35 with or without MLA.