Optimal Chemotherapy for Leukemia: A Model-Based Strategy for Individualized Treatment
Figure 6
MCV model fit to average patient MCV data.
Solid dots represent the data from literature and the solid line shows the model (Eqn. 7) fit with 6-TGN concentration of 158 pmol/8×108 RBCs. The model fits the data well; it reaches the steady state and stays at ΔMCV of ∼8 fL, which is typically observed during 6-MP treatment at Riley Hospital for Children. Error bars represent standard error.