Mef2 Interacts with the Notch Pathway during Adult Muscle Development in Drosophila melanogaster
Figure 5
Reduced activation of the Dl2.6 enhancer in vivo monitored by the expression of the Dl2.6-GFP transgene.
In 21 h APF pupae, muscle fibers are visualized with DAPI staining by the specific arrangement of their nuclei (A, D, asterisks). In a wild-type pupae, Dl2.6 enhancer is activated in developing fibers (B, overlay in C). In pupae overexpressing an RNAi-Mef2 transgene, Dl2.6 enhancer activation is significantly lower than in wild-type (E, overlay in F).