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Promoting Cell Proliferation Using Water Dispersible Germanium Nanowires

Figure 2

Water dispersible Germanium nanowires promote the proliferation of MCF-7 cells.

(A) MCF-7 cells were seeded at 27,000 cells/well, before MTT were carried out over 24 hr as described in the Materials and Methods. Data analysis to determine the level of significance was performed using Welch's t test to determine the level of significance between treatments and control, results were considered to be significant with P<0.05. The results for the above indicate a high degree of significance ***P≤0.001. (B) The normalised viability of MCF-7 cells seeded at 10,000 per well (N>3), was measured after 24 hours of exposure to wires at varying concentrations and measured by WST-1 test. Data analysis was performed using Welch's t test to determine the level of significance.(C) MCF-7 cells were seeded at 10,000 cells/well on increasing concentrations of WDW's for 4 days. Organic cell growth was determined by trypan blue exclusion (n = 5 for each time point and n = 3 for each experiment).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0108006.g002