Efficient Drug Delivery of Paclitaxel Glycoside: A Novel Solubility Gradient Encapsulation into Liposomes Coupled with Immunoliposomes Preparation
Figure 6
Acute toxicity of the drugs in vivo.
gPTX (open circle), gPTX-L (open triangle) or gPTX-IL (open diamond) at a concentration of 150 mg/kg, CEP (open square), or PBS (cross) was intravenously injected into 6-week old female BALB/c mice. A, Changes in body weight. B, Survival rate. Data are presented as the mean ± S.D. (n = 4). gPTX is not shown S.D. after day 3. NSD, no significant difference.