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Mechanism of Inhibition of the Human Sirtuin Enzyme SIRT3 by Nicotinamide: Computational and Experimental Studies

Table 1

Model parameter estimates from global nonlinear fitting of mixed inhibition models for SIRT3 and SIRT1 inhibition by isoNAM (Eq. 2) and NAM (Eq. 1).

Table 1

doi: https://doi.org/10.1371/journal.pone.0107729.t001