Crystal Structure of Transglutaminase 2 with GTP Complex and Amino Acid Sequence Evidence of Evolution of GTP Binding Site
Figure 5
The condition of cysteines at the redox sensor and active site.
A. Cys230 and Cys370 at the redox sensor in TG2 formed a disulfide bond, even under highly reduced conditions. B. Cys277 and Cys336 at the active site in TG2 did not form a disulfide bond.