Effects of GWAS-Associated Genetic Variants on lncRNAs within IBD and T1D Candidate Loci
Figure 5
cis-eQTLs and gene-SNP associations for rs3757247 and rs597325 with BACH2 candidate gene.
(A) The gene SNP association for rs3757247 and BACH2 candidate gene in whole blood. (B, C, D) The gene SNP association for rs597325 and BACH2 in colon transverse, brain cortex and cell line fibroblasts. The gene SNP associations are calculated using linear regression model using Genotype Tissue Expression Portal (GTEx) in the selected tissues with more than 80 samples using a cis window of +/−1 MB around the transcription start site (TSS) at significance level of 0.05. For each gene SNP association plot, p-values are displayed at the bottom.