Effects of GWAS-Associated Genetic Variants on lncRNAs within IBD and T1D Candidate Loci
Figure 4
Regional LD plot for SNP rs3757247 associated with IBD and T1D loci.
The regional LD plot for SNP rs3757247 was calculated using HapMap3 (release 2) in SNAP tool. SNPs are represented as diamonds and the brightness of each SNP is proportional to the r2 threshold value for that SNP. SNPs rs11755527 and rs1847472 had an r2 value of 0.949 (T1D p-valuemeta 5.38e-08, Barrett et al 2009 [52]) and 0.565 (IBD p-valueichip 1.19e-04, IBD p-valuemeta 1.10e-09, Jostins et al 2012 [71]) respectively (shown in red).