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Doxycycline Inducible Kruppel-Like Factor 4 Lentiviral Vector Mediates Mesenchymal to Epithelial Transition in Ovarian Cancer Cells

Figure 5

TGFβ promotes EMT in ovarian cancer cells.

Human ovarian cancer cell lines SKOV3 (A) and OVCAR3 (B) were treated with different doses of TGFβ for 48 h. EMT-associated marker genes, including E-cadherin, snail2, and vimentin were examined using Western blot. Significances were determined by comparing TGFβ treated to non-treatment (*p<0.05, **p<0.01, ***p<0.001).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0105331.g005