Exhaled Aerosol Pattern Discloses Lung Structural Abnormality: A Sensitivity Study Using Computational Modeling and Fractal Analysis
Figure 5
Fractal analysis of exhaled particle distributions using Box Counting method.
Calculation of fractal dimension (FD) of Model A using regression analysis is exemplified in (a). FDs FDs (±SD, n = 5) for the four models are shown in (b) and (c) for the entire image and selected region of interest (ROI), respectively. Significance indicated by *(p<0.05) and **(p<0.01). (d) shows the local FD distribution on a normalized caliber size of 1/6×1/6. The color code was based on the fractal dimension ratio β(i) = FD(i)/FD(A), i = B, C and D. The color pattern is unique to each airway abnormality.