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Identification of Urinary Peptide Biomarkers Associated with Rheumatoid Arthritis

Figure 3

Graphical representation of the frequency distribution of proteases with modified activity associated with RA.

Percentage frequency of peptide occurrences in the down-regulation group is plotted on the x-axis, whereas the percentage frequency of occurrences in the up-regulated group is plotted on the y-axis. Circled data points represent the proteases which activity is the most affected in RA compared to that of healthy controls (see Table 4).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0104625.g003