PDGF-BB Does Not Accelerate Healing in Diabetic Mice with Splinted Skin Wounds
Figure 5
PDGF-BB did not modulate collagen deposition and inflammation development at the wound site in the splinted full thickness dermal wound model in mice.
Percentage collagen content (A) and inflammation score (B) as mean ± SEM in full thickness splinted wounds of db/db mice treated with 0.01% PDGF-BB or vehicle control. No significant differences in percentage collagen content or inflammation score were found (P>0.62).