Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer
Figure 2
CuE suppresses DNA synthesis in MDA-MB-468 and SW527 TNBC cell lines.
A. CuE (0–50–100–200 nM) was used to treat MDA-MB-468 and SW527 cells for 24 h. DNA synthesis was measured by the EdU assay. B. Quantitative data of MDA-MB-468. Percentage of EdU positive proliferating cells vs. total cells is shown. *** p<0.001, student t-test. C. Quantitative data of SW527. Percentage of EdU positive proliferating cells vs. total cells is shown. ** p<0.01, *** p<0.001, student t-test.