Macrophage Control of Phagocytosed Mycobacteria Is Increased by Factors Secreted by Alveolar Epithelial Cells through Nitric Oxide Independent Mechanisms
Figure 8
Inhibiting phagosomal acidification does not affect intracellular killing of BCG.
BMM and PuM were infected with GFP-BCG. After infection, cells were treated with either IFN-γ or AECsup with or without chloroquine (10 µM). Bacterial growth was evaluated by determining RLU. Values are expressed as means ± SD from 5 wells. The data is representative of 2 independent experiments. Differences between treatments analyzed using a one-way ANOVA followed by Bonferroni's Multiple Comparison Test. * significantly different from medium control, P<0.05.