Macrophage Control of Phagocytosed Mycobacteria Is Increased by Factors Secreted by Alveolar Epithelial Cells through Nitric Oxide Independent Mechanisms
Figure 3
IFN-γ and AECsup induce different cytokine profiles in PuM and BMM.
BMM and PuM were infected with GFP-BCG. After infection, cells were left untreated or treated with either IFN-γ or AECsup. Cell culture supernatants were collected at 4 and 24 h after treatments. IL-12, IP-10 and IL-6, levels were measured using ELISA. Values are expressed as means ± SD, from 3 independent experiments. The differences between groups of PuM and BMM were analyzed using a one-way ANOVA followed by Bonferroni‘s Multiple Comparison Test, * Significantly different from medium control, p<0.05.