Carica papaya MicroRNAs Are Responsive to Papaya meleira virus Infection
Figure 7
Relationship of miRNAs to proteasomal degradation.
A schematic showing the relationship of miRNAs 156, 398, 408 and 162 to proteasomal degradation. The red arrows indicate the target genes of miRNAs. Proteasome-ubiquitin degradation involves the binding of ubiquitin (Ubi) to substrate (SUB). Polyubiquitinated proteins are recognised and degraded by the 26S proteasome, which consists of the 19S regulatory particle that recognises, selects and binds the polyubiquitinated proteins, cleaves the polyubiquitin chains and forwards the target polypeptide into the lumen of the 20S core particle, where proteolytic degradation takes place.