Integrative Genomic and Transcriptomic Analysis Identified Candidate Genes Implicated in the Pathogenesis of Hepatosplenic T-Cell Lymphoma
Figure 5
Morphology and ABCB1 expression in HSTL cases detected by IHC.
Immunohistochemical stainings (A–C, anti-CD3; D-F, anti-MDR1/ABCB1) of the typical intrasinusoidal spread (red arrows) by HSTL cells in the bone marrow (A/D, case 4) and spleen (B/E, case 6), respectively, compared to staining pattern in normal spleen (C/F). Pictures captured by Leica DFC290HD camera at 400X. Scale bar = 50 µm.