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Catestatin Increases the Expression of Anti-Apoptotic and Pro-Angiogenetic Factors in the Post-Ischemic Hypertrophied Heart of SHR

Figure 7

S-nitrosylation of calcium channels after 30 min ischemia and 20 min reperfusion.

Western blot analysis of S-nitrosylated proteins in homogenized cardiac ventricles. S-nitrosylation of membrane protein fraction and stripped membrane incubated with an anti L-type calcium channel antibody showing S-nitrosylation at the migration position corresponding to the L-type calcium channel in WKY (panel A) and SHR (panel B) hearts. Individual values were compared to β-actin and the mean value of the Sham group was considered as the reference for all groups, including Sham. *p<0.05 ANOVA followed by Newman–Keuls multiple comparison test, (n = 6 for each group).

Figure 7

doi: https://doi.org/10.1371/journal.pone.0102536.g007