Pesticide Methoxychlor Promotes the Epigenetic Transgenerational Inheritance of Adult-Onset Disease through the Female Germline
Figure 5
Ancestral exposure to methoxychlor promoted adult-onset transgenerational diseases in F4 generation reverse outcross offspring showing female germline transmission.
Incidences of kidney disease in females (panel A), in males (panel B), obesity in females (panel C) and in males (panel D) of the F4 generation outcross (OC) or reverse outcross (ROC) offspring of the control and methoxychlor lineages.