Norepinephrine Stimulates Mobilization of Endothelial Progenitor Cells after Limb Ischemia
Figure 5
Effects of NE on VEGF production.
The blood samples, BM homogenates, skeletal muscle and splenic tissue homogenates were collected from limb ischemic mice and measured by ELISA. NE significantly increased VEGF concentrations in both skeletal muscle and blood sumples, but did not affect it in bone marrow and spleen. Co-treatment of Phentolamine, I127attenuated the increase of VEGF in bone marrow and skeletal muscle, but did not affect it in blood samples and spleen.