A Small Molecule Inhibitor of Human RAD51 Potentiates Breast Cancer Cell Killing by Therapeutic Agents in Mouse Xenografts
Figure 2
B02 increases sensitivity of 3D-growing MDA-MB-231 cells to cisplatin.
A. MDA-MB-231 cells were exposed to cisplatin (in indicated concentrations) in the absence or presence of B02 (5 µM), the colonies were formed in 6-well plates coated with soft agar and stained with 0.005% crystal violet. B. The effect of B02 on survival of MDA-MB-231 cells plotted as a graph. C. The data from panel A plotted as a graph. Error bars represent SD.