A Small Molecule Inhibitor of Human RAD51 Potentiates Breast Cancer Cell Killing by Therapeutic Agents in Mouse Xenografts
Figure 1
B02 increases sensitivity of MDA-MB-231 cells to DNA damaging agents.
A. The structures of B02, doxorubicin, etoposide, topotecan and cisplatin. B. Survival of MDA-MB-231 cells treated with B02 (○) or with indicated agents in the absence (▴) or presence (▾) of B02 (5 µM). Experiments were repeated at least three times. Error bars represent the standard deviation (SD).