Discovery of Novel AKT Inhibitors with Enhanced Anti-Tumor Effects in Combination with the MEK Inhibitor
Figure 5
The impact of GSK2110183 and GSK2141795 on glucose homeostasis in vivo.
Blood glucose (black squares) and plasma insulin (black circles) levels were assayed over time in mice treated with a single efficacious dose of GSK2110183 (30 mg/kg) or GSK2141795 (100 mg/kg). Data represents mean ± s.d.