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Novel Insights into the Regulatory Architecture of CD4+ T Cells in Rheumatoid Arthritis

Figure 4

Transcript Complexity Value analysis of RA risk genes.

TCV from the RA CD4+ T cell and control LCLs analyzed in RA risk genes. A: JAK-STAT signaling pathway. B: T cell receptor signaling pathway. C: TNF signaling pathway. D: Cell adhesion pathway. E: Toll-like receptor signaling pathway. F: Antigen processing and presentation pathway. G: B cell development function pathway. The genes that are framed represent those genes showing significant genomic regulation profiles between RA CD4+ T cells and LCLs (P<0.05).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0100690.g004